SCHEMBL277947

SCHEMBL277947

CC(=O)c1ccnnc1C(C)=O

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
PTGS2 P35354 4/20 0.35
KDM5B Q9UGL1 1/20 0.34
ALDH1A1 P00352 1/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ASPH Q12797 1/20 0.31
KDM8 Q8N371 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30
KCNJ1 P48048 1/20 0.30
KDM4C Q9H3R0 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21408746 0.81 P2RX7 (0.46) KDM5BALDH1A1CA1CA2CA9
SCHEMBL26081243 0.79 TSHR (0.49) ALDH1A1CA12CA1CA2CA9
SCHEMBL25863831 0.78 SMN1; SMN2 (0.35) SMN1; SMN2KDM5BALDH1A1KMT2AMAPT
SCHEMBL25863829 0.78 SMN1; SMN2 (0.45) SMN1; SMN2KDM5BALDH1A1CA9KDM4E
SCHEMBL30937682 0.78 KCNJ1 (0.40) SMN1; SMN2PTGS2ALDH1A1PDE3BPDE3A
SCHEMBL28175265 0.77 SMN1; SMN2 (0.34) SMN1; SMN2KDM5BALDH1A1KMT2AMAPT
SCHEMBL25863834 0.74 ALDH1A1 (0.38) SMN1; SMN2KDM5BALDH1A1CA9KMT2A
SCHEMBL3971849 0.72 KIF11 (0.36) PTGS2KMT2A
SCHEMBL31358932 0.70 CA12 (0.44) ALDH1A1CA12CA1CA2CA9
SCHEMBL28496443 0.70 SMN1; SMN2 (0.35) SMN1; SMN2PTGS2KCNJ1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3781661-B1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-13 EP disclosed
US-11525106-B2 Tetraacetyldiamine and triacetyldiamine derivatives useful as bleach activators DOW GLOBAL TECHNOLOGIES LLC (US) 2022-12-13 US disclosed
US-20210155877-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC 2021-05-27 US disclosed
EP-2572243-B1 POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2021-04-07 EP disclosed
EP-3781661-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS Dow Global Technologies, LLC (US) 2021-02-24 EP disclosed
WO-2019204184-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-24 WO disclosed
EP-2598946-B1 POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2019-04-03 EP disclosed
US-20180163022-A1 NEAR INFRARED ABSORBING CURABLE COMPOSITION, CURED FILM, SOLID IMAGE PICKUP ELEMENT, INFRARED ABSORBER, AND COMPOUND FUJIFILM CORPORATION (JP) 2018-06-14 US disclosed
EP-1720065-B1 Photosensitive lithographic printing plate FUJIFILM CORP (JP) 2017-06-14 EP disclosed
EP-2259141-B1 PROCESS FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2016-11-23 EP disclosed
EP-1112843-A2 Waterless planographic printing plate precursor and production method thereof FUJI PHOTO FILM CO., LTD. (JP) 2001-07-04 EP disclosed
EP-1096314-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-05-02 EP disclosed
EP-0949540-A1 Method for producing lithographic printing plate suitable for laser scan exposure, and photopolymerizable composition FUJI PHOTO FILM CO., LTD (JP) 1999-10-13 EP disclosed
WO-1995000040-A1 STABILISING VOLATILE FLAVOURINGS FIRMENICH SA (CH) 1995-01-05 WO disclosed
US-5069992-A POLYURETHANE CONTAINING CARBOXYL GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1991-12-03 US disclosed
EP-0043853-B1 INJECTION MOLDABLE AMIDE-IMIDE POLYMERS CONTAINING DIVALENT ALIPHATIC RADICALS DERIVED FROM ALIPHATIC DIAMINES AMOCO CORPORATION (US) 1985-11-13 EP disclosed
EP-0043853-A4 INJECTION MOLDABLE AMIDE-IMIDE POLYMERS CONTAINING DIVALENT ALIPHATIC RADICALS DERIVED FROM ALIPHATIC DIAMINES. STANDARD OIL CO (US) 1982-05-28 EP disclosed
US-4323493-A Injection moldable amide-imide polymers contaning divalent aliphatic radicals derived from aliphatic diamines STANDARD OIL COMPANY (INDIANA) (US) 1982-04-06 US disclosed
EP-0043853-A1 INJECTION MOLDABLE AMIDE-IMIDE POLYMERS CONTAINING DIVALENT ALIPHATIC RADICALS DERIVED FROM ALIPHATIC DIAMINES. STANDARD OIL CO (US) 1982-01-20 EP disclosed
WO-1981002015-A1 INJECTION MOLDABLE AMIDE-IMIDE POLYMERS CONTAINING DIVALENT ALIPHATIC RADICALS DERIVED FROM ALIPHATIC DIAMINES STANDARD OIL CO (US) 1981-07-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11525106-B2 Tetraacetyldiamine and triacetyldiamine derivatives useful as bleach activators AADAC, DLAT, NAT10 SMN1; SMN2 4650/4885PTGS2 4218/4885KDM5B 1775/4885
US-20210155877-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS AADAC, DLAT, NAT10 SMN1; SMN2 4650/4885PTGS2 4218/4885KDM5B 1775/4885
US-20180163022-A1 NEAR INFRARED ABSORBING CURABLE COMPOSITION, CURED FILM, SOLID IMAGE PICKUP ELEMENT, INFRARED ABSORBER, AND COMPOUND H1-0, PEAK1, CHRM1 SMN1; SMN2 2069/4885PTGS2 2157/4885KDM5B 774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.