Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126724 | 0.85 | TSHR (0.80) | ALDH1A1TSHRHSD17B10TDP1CA1 | |
| SCHEMBL7655938 | 0.83 | CA1 (0.59) | ALDH1A1TSHRHSD17B10TDP1CA1 | |
| SCHEMBL27864995 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10TDP1CA1 | |
| SCHEMBL27571589 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10TDP1CA1 | |
| SCHEMBL27673382 | 0.83 | LOXL2 (0.61) | ALDH1A1TSHRHSD17B10TDP1CA1 | |
| SCHEMBL1919683 | 0.82 | CA1 (0.50) | ALDH1A1CA1CA2MEN1KMT2A | |
| SCHEMBL23820031 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10TDP1CA1 | |
| SCHEMBL27728611 | 0.81 | TSHR (0.59) | ALDH1A1TSHRHSD17B10TDP1CA1 | |
| SCHEMBL27775507 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10TDP1LOXL2 | |
| SCHEMBL9403236 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHSD17B10TDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107438593-A | THERAPEUTIC COMPOUNDS AND USES THEREOF | 基因泰克公司 | 2017-12-05 | — | — | CN | disclosed |