Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708759 | 0.85 | KMT2A (0.52) | CA1CA2CA12CA9CA14 | |
| SCHEMBL7588248 | 0.85 | ALDH1A1 (0.55) | CA1CA2CA12CA9CA14 | |
| SCHEMBL109451 | 0.84 | CA1 (0.61) | CA1CA2CA12CA9CA14 | |
| SCHEMBL1019092 | 0.83 | CA1 (0.50) | CA1CA2CA12CA9CA14 | |
| SCHEMBL7385067 | 0.83 | CA1 (0.50) | CA1CA2CA12CA9CA14 | |
| SCHEMBL16617577 | 0.83 | CA1 (0.50) | CA1CA2CA12CA9CA14 | |
| SCHEMBL28175299 | 0.82 | ALDH1A1 (0.61) | CA1CA2MEN1KMT2ALOXL2 | |
| SCHEMBL28728633 | 0.82 | CA1 (0.46) | CA1CA2CA12CA9CA14 | |
| SCHEMBL12900838 | 0.81 | CA1 (0.49) | CA1CA2CA12CA9CA14 | |
| Bromide SCHEMBL7535751 | 0.81 | CA1 (0.49) | CA1CA2CA12CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-218945081-U | 4-chloromethyl benzoic acid tert-butyl ester synthesis production line | 上海开荣化工科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-105111214-A | Preparation method of pemetrexed disodium | UNIV JIANGXI AGRICULTURAL | 2015-12-02 | — | — | CN | claimed |
| CN-100575333-C | A kind of preparation method of the 4-chloromethyl benzoic acid tert-butyl ester | UNIV TONGJI | 2009-12-30 | — | — | CN | claimed |
| CN-1907948-A | Preparation method of 4-chloromethyl benzoic acid t-butyl ester | UNIV TONGJI (CN) | 2007-02-07 | — | — | CN | claimed |
| CN-121575222-A | Waste perovskite solar cell recycling and upgrading technology based on supergravity rotating bed | 北京化工大学 | 2026-02-27 | — | — | CN | disclosed |
| US-20260042771-A1 | HETEROCYCLIC COMPOUND FOR INDUCING DEGRADATION OF G12V MUTANT KRAS PROTEIN | ASTELLAS PHARMA INC. (JP) | 2026-02-12 | — | — | US | disclosed |
| US-20250333395-A1 | BENZYLAMIDE DERIVATIVES AS INHIBITORS OF TRANSFORMING GROWTH FACTOR-BETA RECEPTOR I/ALK5 | Agomab Spain, S.L.U. (ES) | 2025-10-30 | — | — | US | disclosed |
| EP-4570795-A1 | HETEROCYCLIC COMPOUND FOR INDUCING DEGRADATION OF G12V MUTANT KRAS PROTEIN | Astellas Pharma, Inc. (JP) | 2025-06-18 | — | — | EP | disclosed |
| US-12297186-B2 | Benzylamide derivatives as inhibitors of transforming growth factor-beta receptor I/ALK5 | Agomab Spain, S.L.U. (ES) | 2025-05-13 | — | — | US | disclosed |
| CN-119320386-A | METTL3 inhibitor, preparation method and application thereof | 郑州大学第一附属医院 | 2025-01-17 | — | — | CN | disclosed |
| WO-2024126777-A1 | HETEROAROMATIC COMPOUNDS | ASTRAZENECA AB (SE) | 2024-06-20 | — | — | WO | disclosed |
| CN-113372215-B | Novel esterification method for synthesizing p-halomethyl benzoate | 吉林大学 | 2024-05-24 | — | — | CN | disclosed |
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2009-11-19 | — | — | US | disclosed |
| CN-1907948-A | Preparation method of 4-chloromethyl benzoic acid t-butyl ester | UNIV TONGJI (CN) | 2007-02-07 | — | — | CN | disclosed |
| CN-1907948-A | Preparation method of 4-chloromethyl benzoic acid t-butyl ester | UNIV TONGJI (CN) | 2007-02-07 | — | — | CN | disclosed |
| CN-1907948-A | Preparation method of 4-chloromethyl benzoic acid t-butyl ester | UNIV TONGJI (CN) | 2007-02-07 | — | — | CN | disclosed |
| EP-0486937-B1 | Hydrazone derivatives, processes for production thereof, and uses thereof | NIHON NOHYAKU CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5358965-A | Agricultural and horticultural insecticides, activity against moths and beetles | NIHON NOHYAKU CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| US-5304573-A | Insecticides | NIHON NOHYAKU CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0486937-A1 | Hydrazone derivatives, processes for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042771-A1 | HETEROCYCLIC COMPOUND FOR INDUCING DEGRADATION OF G12V MUTANT KRAS PROTEIN | KRAS, NRAS, HRAS | CA1 2586/4885CA2 2977/4885CA12 2845/4885 |
| US-12297186-B2 | Benzylamide derivatives as inhibitors of transforming growth factor-beta receptor I/ALK5 | TGFBR2, TGFBR1, ACVR1 | CA1 4684/4885CA2 2326/4885CA12 3476/4885 |
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | PCCA, PPP2CA, HMGCR | CA1 1238/4885CA2 772/4885CA12 1514/4885 |
| US-20250333395-A1 | BENZYLAMIDE DERIVATIVES AS INHIBITORS OF TRANSFORMING GROWTH FACTOR-BETA RECEPTOR I/ALK5 | TGFBR2, TGFBR1, ACVR1 | CA1 4684/4885CA2 2326/4885CA12 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.