Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28060182 | 0.89 | KDM4A (0.36) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL21738035 | 0.85 | HTT (0.47) | CA1CA2LMNAMEN1GAA | |
| SCHEMBL26328784 | 0.76 | KDM4E (0.43) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL1585659 | 0.76 | L3MBTL1 (0.47) | KDM4ELMNAKDM4AHDAC3HDAC1 | |
| SCHEMBL8041524 | 0.75 | HDAC3 (0.47) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL25063332 | 0.75 | GAA (0.44) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL16020352 | 0.75 | HDAC3 (0.48) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL215719 | 0.75 | HDAC3 (0.51) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL15248092 | 0.74 | GLS (0.43) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL10042081 | 0.74 | GLS (0.43) | CA12CA1CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395324-B | Mi Zuo Bing oxadiazoles and imidazo thiadiazoles derivative | 阿瑞斯贸易股份有限公司 | 2017-09-12 | — | — | CN | disclosed |