Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977598 | 0.88 | KDM4E (0.49) | KDM4ELMNAHTTKDM4ANAMPT | |
| SCHEMBL16628028 | 0.81 | KDM4E (0.44) | KDM4ELMNAHTTKDM4ANAMPT | |
| SCHEMBL16625930 | 0.81 | KDM4E (0.44) | KDM4ELMNAHTTKDM4ANAMPT | |
| SCHEMBL16616006 | 0.78 | NAMPT (0.53) | NAMPTL3MBTL1CA1CA2TDP1 | |
| SCHEMBL17035934 | 0.78 | KDM4A (0.47) | KDM4ELMNAKDM4ANAMPTL3MBTL1 | |
| SCHEMBL26328793 | 0.78 | HTT (0.47) | KDM4ELMNAHTTKDM4ANAMPT | |
| SCHEMBL28175608 | 0.76 | CA12 (0.41) | KDM4ELMNAHTTKDM4ANAMPT | |
| SCHEMBL25497278 | 0.76 | HDAC1 (0.47) | KDM4ANAMPTCYP1A2CA12CA1 | |
| SCHEMBL17107898 | 0.75 | L3MBTL1 (0.50) | KDM4ELMNAKDM4AL3MBTL1CYP1A2 | |
| SCHEMBL13865274 | 0.75 | L3MBTL1 (0.44) | KDM4ELMNAKDM4ANAMPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | UNIVERSITY OF DELAWARE (US) | 2023-09-26 | — | — | US | disclosed |
| US-20220106278-A1 | REAGENTS AND METHODS FOR TETRAZINE SYNTHESIS | UNIVERSITY OF DELAWARE (US) | 2022-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767302-B2 | Reagents and methods for tetrazine synthesis | TST, CYP4F8, CYP4Z1 | KDM4E 1634/4885LMNA 3980/4885HTT 1626/4885 |
| US-20220106278-A1 | REAGENTS AND METHODS FOR TETRAZINE SYNTHESIS | TST, CYP4F8, CYP4Z1 | KDM4E 1634/4885LMNA 3980/4885HTT 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.