Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.49 |
| ▸ | TUBB | P07437 | 4/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448977 | 0.85 | MAPT (0.55) | PKMLMNATUBB4ATUBBTUBA3C | |
| SCHEMBL27686642 | 0.84 | PKM (0.52) | PKMLMNATUBB4ATUBBTUBA3C | |
| SCHEMBL890810 | 0.83 | PKM (1.00) | PKMLMNAMAPTKDM4EHSD17B10 | |
| SCHEMBL10436235 | 0.81 | TUBB4A (0.54) | PKMLMNATUBB4ATUBBTUBA3C | |
| SCHEMBL2137968 | 0.81 | MAPT (0.58) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL27462903 | 0.80 | MAPT (0.56) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7434951 | 0.80 | LMNA (0.51) | PKMLMNATUBB4ATUBBTUBA3C | |
| SCHEMBL27595882 | 0.79 | LMNA (0.69) | LMNAMAPTKDM4EHSD17B10CYP3A4 | |
| SCHEMBL11742991 | 0.79 | MAPT (0.60) | LMNAMAPTKDM4EHSD17B10CYP3A4 | |
| SCHEMBL30498928 | 0.79 | PKM (0.75) | PKMLMNAMAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541748-B | 1,3,4 oxadiazole Mannich base class compounds and preparation and application containing piperazine | 南开大学 | 2017-09-12 | — | — | CN | claimed |