Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 8/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.38 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175688 | 1.00 | MMP3 (0.50) | MMP3DPP4DPP8DPP9FAP | |
| SCHEMBL7976372 | 0.98 | MMP3 (0.49) | MMP3DPP4DPP8DPP9FAP | |
| SCHEMBL18347968 | 0.84 | MMP3 (0.53) | MMP3DPP4CHRM5CHRM3CA2 | |
| SCHEMBL25794713 | 0.75 | MMP3 (0.46) | MMP3DPP4 | |
| SCHEMBL21013611 | 0.74 | MMP3 (0.44) | MMP3DPP4CHRM5CHRM3 | |
| SCHEMBL20197951 | 0.73 | — | — | |
| SCHEMBL4097865 | 0.73 | — | — | |
| SCHEMBL7458218 | 0.72 | — | — | |
| SCHEMBL27323442 | 0.72 | CA2 (0.44) | MMP3DPP4CA2CHKA | |
| SCHEMBL2505898 | 0.71 | MMP3 (0.41) | MMP3CA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781261-B | The macrocyclic hcv inhibitors of flaviviridae | 吉利德科学公司 | 2017-08-25 | — | — | CN | disclosed |