Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 5/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.37 |
| ▸ | FAP | Q12884 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175689 | 0.98 | MMP3 (0.50) | MMP3DPP4DPP7FAPPREP | |
| SCHEMBL28175688 | 0.98 | MMP3 (0.50) | MMP3DPP4DPP7FAPPREP | |
| SCHEMBL18347968 | 0.82 | MMP3 (0.53) | MMP3DPP4CA2CHKACHRM5 | |
| SCHEMBL2505898 | 0.74 | MMP3 (0.41) | MMP3CA2CHKA | |
| SCHEMBL2382694 | 0.74 | CA2 (0.40) | MMP3DPP4CA2CHKA | |
| SCHEMBL25794713 | 0.74 | MMP3 (0.46) | MMP3DPP4 | |
| SCHEMBL3466500 | 0.73 | CA2 (0.43) | MMP3CA2CHKA | |
| SCHEMBL1919225 | 0.73 | CA2 (0.43) | MMP3CA2CHKA | |
| SCHEMBL21013611 | 0.73 | MMP3 (0.44) | MMP3DPP4CHRM5CHRM3 | |
| SCHEMBL20299686 | 0.73 | KCNQ2 (0.43) | MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | disclosed |