Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL16469140 | 1.00 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Propene SCHEMBL5472607 | 1.00 | TSHR (0.61) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL38483 | 0.96 | — | — | |
| SCHEMBL15841507 | 0.93 | TSHR (0.64) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Ethylene SCHEMBL15417912 | 0.93 | TSHR (0.64) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Ethylene SCHEMBL23130998 | 0.93 | TSHR (0.64) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Propene SCHEMBL11227474 | 0.91 | TSHR (0.73) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL138941 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL864613 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1523809 | 0.89 | TSHR (0.79) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904408-B1 | SOFT INTRAOCULAR LENS MATERIAL AND SOFT INTRAOCULAR LENS | NIDEK KK (JP) | 2024-11-20 | — | — | EP | disclosed |
| CN-115975105-B | Soft intraocular lens material and soft intraocular lens | 株式会社尼德克 | 2024-11-19 | — | — | CN | disclosed |
| CN-115975105-A | Soft intraocular lens material and soft intraocular lens | 株式会社尼德克 | 2023-04-18 | — | — | CN | disclosed |
| CN-113195563-B | Soft intraocular lens material and soft intraocular lens | 株式会社尼德克 | 2022-12-23 | — | — | CN | disclosed |
| EP-3409703-B1 | WATER ABSORBENT RESIN HAVING SILOXANE SKELETON, AND COSMETIC INCLUDING SAME | SHINETSU CHEMICAL CO (JP) | 2021-11-10 | — | — | EP | disclosed |
| EP-3904408-A1 | SOFT INTRAOCULAR LENS MATERIAL AND SOFT INTRAOCULAR LENS | Nidek Co., Ltd. (JP) | 2021-11-03 | — | — | EP | disclosed |
| CN-113195563-A | Soft intraocular lens material and soft intraocular lens | 株式会社尼德克 | 2021-07-30 | — | — | CN | disclosed |
| CN-108602930-B | Water-absorbent resin having siloxane skeleton and cosmetic material containing the same | 信越化学工业株式会社 | 2020-11-17 | — | — | CN | disclosed |
| US-10786440-B2 | Water absorbing resin having siloxane skeleton and cosmetic containing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-09-29 | — | — | US | disclosed |
| WO-2020138346-A1 | SOFT INTRAOCULAR LENS MATERIAL AND SOFT INTRAOCULAR LENS | 株式会社ニデック | 2020-07-02 | — | — | WO | disclosed |
| CN-108602930-A | Water-absorbing resins with siloxane backbone and the cosmetic for including the water-absorbing resins | 信越化学工业株式会社 | 2018-09-28 | — | — | CN | disclosed |
| CN-108070325-A | Hydrophilic and hydrophobic amphoteric patch structure | 高雄大学 | 2018-05-25 | — | — | CN | disclosed |
| US-9012028-B2 | Optical resin composition, optical resin material using the same, optical | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| EP-2796504-A2 | Optical resin composition, optical resin material using the same, optical filter for image display device, and image display device | Hitachi Chemical Co., Ltd. (JP) | 2014-10-29 | — | — | EP | disclosed |
| US-8859683-B2 | Optical resin composition, optical resin material using the same, optical filter for image display device, and image display device | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2014-10-14 | — | — | US | disclosed |
| US-8653200-B2 | Optical resin composition, optical resin material using the same, optical filter for image display device, and image display device | HITACHI CHEMICAL CO., LTD. (JP) | 2014-02-18 | — | — | US | disclosed |
| US-20140023799-A1 | OPTICAL RESIN COMPOSITION, OPTICAL RESIN MATERIAL USING THE SAME, OPTICAL | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2014-01-23 | — | — | US | disclosed |
| US-20120120347-A1 | OPTICAL RESIN COMPOSITION, OPTICAL RESIN MATERIAL USING THE SAME, OPTICAL FILTER FOR IMAGE DISPLAY DEVICE, AND IMAGE DISPLAY DEVICE | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20100247940-A1 | Optical resin composition, optical resin material using the same, optical filter for image display device, and image display device | HITACHI CHEMICAL CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2053087-A1 | RESIN COMPOSITION FOR OPTICAL USE, RESIN MATERIAL FOR OPTICAL USE USING THE SAME, OPTICAL FILTER FOR IMAGE DISPLAY DEVICE, AND IMAGE DISPLAY DEVICE | Hitachi Chemical Co., Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10786440-B2 | Water absorbing resin having siloxane skeleton and cosmetic containing the same | ILK, COL2A1, COL1A1 | TSHR 2394/4885ALDH1A1 841/4885TP53 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.