Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382816 | 0.81 | NR1H2 (0.47) | KDM4EL3MBTL1POLQLMNAPPARA | |
| SCHEMBL28176917 | 0.79 | RXRA (0.44) | POLQRXRARXRBRXRG | |
| SCHEMBL28155357 | 0.78 | SIRT2 (0.39) | POLQEPHX2RXRARXRBRXRG | |
| SCHEMBL28176921 | 0.77 | SLC6A2 (0.37) | POLQRXRARXRBRXRGAR | |
| SCHEMBL28175906 | 0.77 | FFAR4 (0.43) | PPARAPPARGPPARDEPHX2RXRA | |
| SCHEMBL16054403 | 0.75 | ALDH1A1 (0.45) | L3MBTL1LMNA | |
| SCHEMBL16054404 | 0.75 | ALDH1A1 (0.45) | L3MBTL1LMNA | |
| SCHEMBL19073460 | 0.73 | IDO1 (0.34) | POLQ | |
| SCHEMBL28210229 | 0.72 | CES2 (0.46) | KDM4ERXRARXRB | |
| SCHEMBL28851037 | 0.70 | CYP4F2 (0.45) | L3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107250110-A | The noval chemical compound of (RET) inhibitor is reset as transfection | 葛兰素史克知识产权发展有限公司 | 2017-10-13 | — | — | CN | disclosed |