Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288435 | 0.86 | HDAC8 (0.58) | HDAC8ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7205018 | 0.86 | HDAC8 (0.58) | HDAC8ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL18538460 | 0.81 | HDAC8 (0.79) | HDAC8ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL13388605 | 0.79 | ALDH1A1 (0.49) | HDAC8ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL13388607 | 0.79 | ALDH1A1 (0.49) | HDAC8ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL4592405 | 0.79 | MAPT (0.68) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4592398 | 0.79 | MAPT (0.68) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL18069259 | 0.78 | ALDH1A1 (0.49) | HDAC8ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL7098090 | 0.77 | MAPT (0.71) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL751457 | 0.77 | MAPT (0.60) | HDAC8ALDH1A1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107690329-A | PITUITOUS SILICONE EMULSIONS | 美国道康宁公司 | 2018-02-13 | — | — | CN | disclosed |
| CN-107207740-A | The method for preparing the particle of functionalization | 美国道康宁公司 | 2017-09-26 | — | — | CN | disclosed |