SCHEMBL2817848

SCHEMBL2817848

CCCC[Si](CS)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
DNM1 Q05193 8/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7937005 0.84
SCHEMBL109247 0.84 LMNA (0.37) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL7107541 0.83 LMNA (0.31) LMNA
SCHEMBL705772 0.81 LMNA (0.35) LMNADNM1MEN1KMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL27832266 0.81 LMNA (0.35) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL703460 0.81 LMNA (0.35) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL705913 0.81 LMNA (0.35) LMNADNM1MEN1KMT2AALDH1A1
SCHEMBL23040429 0.79 LMNA (0.34) LMNATSHR
SCHEMBL703797 0.79 LMNA (0.34) LMNATSHR
SCHEMBL3242411 0.79 LMNA (0.39) LMNADNM1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372514-B2 Moisture-curing composition comprising at least two polymers having silane groups SIKA TECHNOLOGY AG (CH) 2013-02-12 US disclosed
US-20100247929-A1 MOISTURE-CURING COMPOSITION COMPRISING AT LEAST TWO POLYMERS HAVING SILANE GROUPS SIKA TECHNOLOGY AG (CH) 2010-09-30 US disclosed
EP-2212365-A1 MOISTURE-CURING COMPOSITION, COMPRISING POLYMERS HAVING AT LEAST TWO SILANE GROUPS Sika Technology AG (CH) 2010-08-04 EP disclosed
WO-2009065654-A1 MOISTURE-CURING COMPOSITION, COMPRISING POLYMERS HAVING AT LEAST TWO SILANE GROUPS SIKA TECHNOLOGY AG (CH) 2009-05-28 WO disclosed