Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Mequinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroquinone SCHEMBL28180795 | 0.89 | ALOX15 (0.62) | ALOX15ESR2CA1CA2CA12 | |
| Mequinol SCHEMBL8991678 | 0.84 | ESR2 (0.53) | ESR2LTA4HCA1CA2CA12 | |
| Mequinol SCHEMBL2859194 | 0.81 | ESR2 (0.64) | ESR2LTA4HCA1CA2MAPT | |
| Phenol SCHEMBL9506782 | 0.79 | ALOX15 (0.60) | ALOX15ESR2CA1CA2CA12 | |
| Phenol SCHEMBL1348208 | 0.79 | ALOX15 (0.60) | ALOX15ESR2CA1CA2CA12 | |
| Phenol SCHEMBL29043743 | 0.78 | ALOX15 (0.58) | ALOX15ESR2CA1CA2CA12 | |
| SCHEMBL155140 | 0.78 | ALDH1A1 (0.57) | CA1CA2NPC1MAPTRAB9A | |
| Phenol SCHEMBL5023434 | 0.76 | ALOX15 (0.56) | ALOX15ESR2CA1CA2CA12 | |
| Mequinol SCHEMBL481721 | 0.76 | LTA4H (0.70) | ESR2LTA4HCA1CA2CA12 | |
| Mequinol SCHEMBL10605062 | 0.76 | ESR2 (0.70) | ESR2LTA4HCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105086916-B | A kind of double curing adhesives of high printing opacity UV moistures | 天津沃尔提莫新材料技术股份有限公司 | 2017-10-17 | — | — | CN | disclosed |