Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706548 | 0.89 | PTGS2 (0.56) | PTGS2ALOX5PTGS1 | |
| SCHEMBL5203365 | 0.86 | PTGS2 (0.57) | PTGS2ALOX5PTGS1 | |
| SCHEMBL6885606 | 0.86 | PTGS2 (0.57) | PTGS2ALOX5PTGS1 | |
| SCHEMBL5202252 | 0.79 | PTGS2 (0.53) | PTGS2ALOX5PTGS1 | |
| SCHEMBL6880090 | 0.79 | PTGS2 (0.53) | PTGS2ALOX5PTGS1 | |
| SCHEMBL6884932 | 0.75 | PTGS2 (0.62) | PTGS2ALOX5PTGS1 | |
| SCHEMBL5205884 | 0.74 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL7706947 | 0.73 | PTGS2 (0.59) | PTGS2ALOX5PTGS1 | |
| SCHEMBL5201916 | 0.73 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6883989 | 0.73 | PTGS2 (0.64) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153055-B | Propenyl benzene is acylated the triazole derivatives of 1,5 diaryl 1,2,4, its preparation method and medical usage | 中国药科大学 | 2017-10-24 | — | — | CN | disclosed |