Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 14/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190488 | 0.87 | GAA (0.62) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL21645801 | 0.83 | GAA (0.62) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL8594791 | 0.82 | SRC (0.54) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL6860761 | 0.78 | GAA (0.49) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL7192591 | 0.76 | GAA (0.57) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL27994626 | 0.76 | GAA (0.57) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL3931144 | 0.76 | GAA (0.57) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL1230426 | 0.75 | GAA (1.00) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL565925 | 0.74 | GAA (0.69) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL29515065 | 0.74 | GAA (0.69) | GAAKDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693673-B | Containing 2,4 dinitrobenzenesulfonyl coumarin kind compounds and preparation method and application | 华东理工大学 | 2017-11-14 | — | — | CN | disclosed |