SCHEMBL7192591

SCHEMBL7192591

C=CCc1c(N)c(=O)oc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 14/20 0.57
KDM4E B2RXH2 7/20 0.57
ALDH1A1 P00352 6/20 0.57
MAPT P10636 5/20 0.49
HSD17B10 Q99714 2/20 0.49
HPGD P15428 2/20 0.47
ALOX15 P16050 1/20 0.47
POLB P06746 2/20 0.46
AGTR1 P30556 1/20 0.46
TAAR1 Q96RJ0 1/20 0.45
VKORC1 Q9BQB6 1/20 0.44
LMNA P02545 3/20 0.44
MEN1 O00255 1/20 0.44
ABCB11 O95342 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
NQO1 P15559 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3988877 0.88 GAA (0.57) GAAKDM4EALDH1A1MAPTHSD17B10
SCHEMBL4274245 0.79 KDM4E (0.39) GAAKDM4EALDH1A1MAPTHSD17B10
SCHEMBL4190488 0.79 GAA (0.62) GAAKDM4EALDH1A1MAPTHSD17B10
SCHEMBL21645801 0.79 GAA (0.62) GAAKDM4EALDH1A1MAPTHSD17B10
SCHEMBL4353785 0.79 VKORC1 (0.43) GAAKDM4EALDH1A1VKORC1LMNA
SCHEMBL7143392 0.78 VKORC1 (0.71) KDM4EALDH1A1VKORC1LMNAMEN1
SCHEMBL5478821 0.78 VKORC1 (0.51) GAAKDM4EALDH1A1MAPTHSD17B10
SCHEMBL28181695 0.76 GAA (0.59) GAAKDM4EALDH1A1MAPTHSD17B10
SCHEMBL27994626 0.75 GAA (0.57) GAAKDM4EALDH1A1MAPTHSD17B10
SCHEMBL3931144 0.75 GAA (0.57) GAAKDM4EALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100534633-C Vehicle identification marking system MILTON RODRIGUEZ (US) 2009-09-02 CN disclosed
CN-1886205-A Vehicle identification marking system MILTON RODRIGUEZ (US) 2006-12-27 CN disclosed
EP-1370291-A1 DEVICE AND METHOD FOR THE PHOTODYNAMIC DIAGNOSIS OF TUMOR TISSUE University of Utah Research Foundation (US) 2003-12-17 EP disclosed
WO-2002074339-A1 DEVEICE AND METHOD FOR THE PHOTODYNAMIC DIAGNOSIS OF TUMOR TISSUE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2002-09-26 WO disclosed