Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 15/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181695 | 0.87 | GAA (0.59) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL21645801 | 0.83 | GAA (0.62) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL3931144 | 0.79 | GAA (0.57) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL27994626 | 0.79 | GAA (0.57) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL7192591 | 0.79 | GAA (0.57) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL1230426 | 0.77 | GAA (1.00) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL8594791 | 0.75 | SRC (0.54) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL28320998 | 0.73 | GAA (0.69) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL11693383 | 0.73 | GAA (0.69) | GAAKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL31178946 | 0.73 | GAA (0.69) | GAAKDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841784-A4 | VACUOLE TARGETING PEPTIDE AND NUCLEIC ACID | SUGAR INDUSTRY INNOVATION PTY (AU) | 2009-02-25 | — | — | EP | disclosed |
| EP-1841784-A1 | VACUOLE TARGETING PEPTIDE AND NUCLEIC ACID | Sugar Industry Innovation Pty Ltd (AU) | 2007-10-10 | — | — | EP | disclosed |
| EP-1707622-A1 | USE OF COMPOUNDS THAT REGULATE HDAC6 TUBULIN DEACETYLASE ACTIVITY IN THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS, METHOD OF IDENTIFYING THE AFOREMENTIONED REGULATING COMPOUNDS, SAID PHARMACEUTICAL COMPOUNDS AND APPLICATIONS THEREOF | UNIVERSIDAD AUTONOMA DE MADRID CIUDAD UNIVERSITARIA CANTOBLANCO (ES) | 2006-10-04 | — | — | EP | disclosed |
| WO-2006066358-A1 | VACUOLE TARGETING PEPTIDE AND NUCLEIC ACID | SUGAR INDUSTRY INNOVATION PTY LTD (AU) | 2006-06-29 | — | — | WO | disclosed |