Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27200631 | 0.91 | MEP1B (0.60) | MEP1BUSP2TSHRFFAR1F2RL1 | |
| SCHEMBL28987474 | 0.87 | USP2 (0.53) | MEP1BUSP2TSHRFFAR1F2RL1 | |
| SCHEMBL9172532 | 0.82 | MEP1B (0.58) | MEP1BUSP2TSHRFFAR1ACHE | |
| SCHEMBL9540871 | 0.81 | ACHE (0.56) | MEP1BUSP2TSHRFFAR1ACHE | |
| SCHEMBL21665226 | 0.80 | HDAC8 (0.47) | MEP1BTSHRFFAR1SMN1; SMN2HTT | |
| SCHEMBL23857640 | 0.80 | MEP1B (0.58) | MEP1BF2RL1KDM4EACHESMN1; SMN2 | |
| SCHEMBL18646559 | 0.80 | TSHR (0.62) | MEP1BUSP2TSHRFFAR1F2RL1 | |
| SCHEMBL18942071 | 0.79 | ALDH1A1 (0.54) | MEP1BUSP2TSHRFFAR1KDM4E | |
| SCHEMBL20952391 | 0.78 | MEP1B (0.73) | MEP1BMEP1A | |
| SCHEMBL10150374 | 0.77 | ALDH1A1 (0.57) | KDM4EACHEALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107304204-B | Method for preparing N-heterocyclic compound | 广东东阳光药业有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-107304204-A | A kind of method for preparing N- heterocyclic compounds | 广东东阳光药业有限公司 | 2017-10-31 | — | — | CN | disclosed |