Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 8/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 8/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799678 | 0.72 | ALDH1A1 (0.63) | PDE10AMAPTPOLBHSD17B10KDM4E | |
| SCHEMBL28446161 | 0.70 | ALDH1A1 (0.62) | PDE10AMAPTPOLBHSD17B10KDM4E | |
| SCHEMBL1075533 | 0.69 | PDE10A (0.50) | PDE10AMAPTPOLBHSD17B10KDM4E | |
| SCHEMBL13528568 | 0.69 | ALDH1A1 (0.68) | PDE10AMAPTPOLBHSD17B10KDM4E | |
| SCHEMBL3163523 | 0.68 | ALDH1A1 (0.54) | PDE10AMAPTPOLBHSD17B10KDM4E | |
| SCHEMBL3060017 | 0.67 | KDM4E (0.58) | PDE10AMAPTPOLBHSD17B10KDM4E | |
| SCHEMBL293854 | 0.67 | PDE10A (0.47) | PDE10AMAPTPOLBHSD17B10KDM4E | |
| SCHEMBL8221447 | 0.66 | METAP2 (1.00) | METAP2IDO1KEAP1SIRT3METAP1 | |
| SCHEMBL7914418 | 0.65 | PDE10A (1.00) | PDE10AMAPTPOLBHSD17B10KDM4E | |
| SCHEMBL645061 | 0.65 | PDE10A (0.64) | PDE10AMAPTPOLBHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669569-B | A kind of synthetic method of the triazole compounds of NH 1,2,3 | 武汉工程大学 | 2017-12-12 | — | — | CN | disclosed |
| CN-105669569-A | Synthesis method of NH-1,2,3-triazole compound | 武汉工程大学 | 2016-06-15 | — | — | CN | disclosed |