Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.62 |
| ▸ | BLM | P54132 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | PKM | P14618 | 3/20 | 0.62 |
| ▸ | CASP1 | P29466 | 3/20 | 0.62 |
| ▸ | CASP7 | P55210 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.62 |
| ▸ | RECQL | P46063 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352544 | 0.78 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL2114343 | 0.77 | MAPT (1.00) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL31064873 | 0.73 | ALDH1A1 (0.65) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL1799678 | 0.73 | ALDH1A1 (0.63) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL11624096 | 0.71 | KDM4E (0.50) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL27512201 | 0.71 | KDM4E (0.50) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL29771573 | 0.70 | KDM4E (0.56) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL3256522 | 0.70 | KDM4E (0.56) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL28186115 | 0.70 | METAP2 (0.49) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL27734202 | 0.70 | MEN1 (1.00) | ALDH1A1POLBMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438376-B | 4, 5-diheteroaryl substituted triazole compound and preparation method and application thereof | 扬州工业职业技术学院 | 2020-09-04 | — | — | CN | disclosed |