SCHEMBL28186367

SCHEMBL28186367

C=C(C)C(=O)OCc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.51
ELANE P08246 3/20 0.50
AKR1C3 P42330 1/20 0.42
ALDH1A1 P00352 5/20 0.42
CYP2C19 P33261 3/20 0.42
CYP2C9 P11712 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAPT P10636 5/20 0.41
MAPK1 P28482 2/20 0.41
HPGD P15428 3/20 0.41
HTT P42858 3/20 0.41
CYP19A1 P11511 1/20 0.41
GAA P10253 1/20 0.40
LMNA P02545 2/20 0.39
PGR P06401 1/20 0.39
CYP2D6 P10635 1/20 0.39
SLC6A2 P23975 1/20 0.39
PDE4A P27815 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7077409 0.86 HTT (0.48) ELANEALDH1A1CYP2C9HPGDHTT
SCHEMBL14480229 0.86 ELANE (0.48) L3MBTL1ELANEAKR1C3ALDH1A1CYP2C19
SCHEMBL28819327 0.83 TDP1 (0.47) L3MBTL1ELANEAKR1C3ALDH1A1MAPT
SCHEMBL11348824 0.83 L3MBTL1 (0.49) L3MBTL1AKR1C3ALDH1A1CYP2C19CYP2C9
SCHEMBL9413234 0.82 L3MBTL1 (0.46) L3MBTL1ELANEAKR1C3ALDH1A1CYP2C19
SCHEMBL4202389 0.82 TSHR (0.44) ELANEALDH1A1MAPTHTTLMNA
SCHEMBL29577269 0.82 TSHR (0.44) ELANEALDH1A1MAPTHTTLMNA
SCHEMBL9821433 0.81 ELANE (0.44) L3MBTL1ELANEAKR1C3MAPTMAPK1
SCHEMBL17940800 0.80 HPGD (0.46) ELANEALDH1A1CYP2C19CYP2C9CYP1A2
SCHEMBL14306620 0.79 ALDH1A1 (0.40) L3MBTL1ELANEALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699184-B (methyl) acrylic-based compositions, coating and solidified body comprising being somebody's turn to do (methyl) acrylic-based compositions 三菱瓦斯化学株式会社 2019-08-09 CN disclosed
CN-109790366-A The manufacturing method of (methyl) acrylic copolymer, resin combination, its formed body and formed body 三菱瓦斯化学株式会社 2019-05-21 CN disclosed
CN-107406654-B Resin composition and molded article using same 三菱瓦斯化学株式会社 2019-03-08 CN disclosed
CN-108699184-A (methyl) acrylic-based compositions include the coating and firming body for being somebody's turn to do (methyl) acrylic-based compositions 三菱瓦斯化学株式会社 2018-10-23 CN disclosed
CN-107406654-A Resin composition and molded article using same 三菱瓦斯化学株式会社 2017-11-28 CN disclosed