SCHEMBL7077409

SCHEMBL7077409

C=C(C)C(=O)OCc1ccccc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.48
TP53 P04637 1/20 0.48
MRGPRX4 Q96LA9 1/20 0.47
FOLH1 Q04609 3/20 0.45
TDP1 Q9NUW8 2/20 0.44
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
ALDH1A1 P00352 6/20 0.42
TSHR P16473 2/20 0.41
CYP2C9 P11712 1/20 0.41
HIF1A Q16665 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ESR1 P03372 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
HMGB1 P09429 1/20 0.41
HPGD P15428 1/20 0.41
GGT1 P19440 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19611833 0.88 FOLH1 (0.40) HTTTP53MRGPRX4FOLH1TDP1
SCHEMBL28186367 0.86 L3MBTL1 (0.51) HTTTDP1POLBAPEX1ALDH1A1
SCHEMBL29577269 0.86 TSHR (0.44) HTTTDP1POLBAPEX1ALDH1A1
SCHEMBL4202389 0.86 TSHR (0.44) HTTTDP1POLBAPEX1ALDH1A1
SCHEMBL28187047 0.86 HNF4A (0.39) HTTTP53MRGPRX4FOLH1TDP1
SCHEMBL11963926 0.85 CYP2C9 (0.41) HTTTP53MRGPRX4TDP1POLB
SCHEMBL21112016 0.84 FOLH1 (0.50) HTTTP53FOLH1TDP1POLB
SCHEMBL17940800 0.84 HPGD (0.46) TP53TDP1ALDH1A1TSHRCYP2C9
SCHEMBL14306620 0.83 ALDH1A1 (0.40) HTTTP53MRGPRX4TDP1POLB
SCHEMBL38654957 0.83 ALDH1A1 (0.58) HTTTP53MRGPRX4FOLH1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030225230-A1 Polymers for antifouling coatings and a process for the preparation thereof JOTUN A/S 2003-12-04 US claimed
EP-0833870-B1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN AS (NO) 1999-09-08 EP claimed
EP-0833870-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF Jotun A/S (NO) 1998-04-08 EP claimed
WO-1996041842-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN A/S (NO) 1996-12-27 WO claimed
CN-105705580-A (meth) acrylic copolymer, resin composition, and molded article thereof 三菱瓦斯化学株式会社 2016-06-22 CN disclosed
US-20030225230-A1 Polymers for antifouling coatings and a process for the preparation thereof JOTUN A/S 2003-12-04 US disclosed
EP-0833870-B1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN AS (NO) 1999-09-08 EP disclosed
EP-0833870-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF Jotun A/S (NO) 1998-04-08 EP disclosed
WO-1996041842-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN A/S (NO) 1996-12-27 WO disclosed