Acrylic Acid

Acrylic Acid

SCHEMBL28186901

C=CC(=O)O.C=CN(C=CC#N)c1ccccc1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.34
NPSR1 Q6W5P4 1/20 0.32
TGM2 P21980 1/20 0.32
LMNA P02545 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8060943 0.76 HDAC3 (0.41) AKT1NPSR1TGM2LMNAHDAC3
Acrylic Acid SCHEMBL5161326 0.70 AKT1 (0.45) AKT1NPSR1TGM2LMNAHDAC3
Acrylic Acid SCHEMBL14672542 0.69 AKT1 (0.48) AKT1NPSR1TGM2LMNAHDAC3
SCHEMBL296620 0.69 ALDH1A1 (0.48) AKT1NPSR1MEN1ALDH1A1POLB
Acrylic Acid SCHEMBL237879 0.68 MAOB (0.47) LMNAHDAC3HDAC4HDAC1HDAC7
Acrylic Acid SCHEMBL1720420 0.68 MAOB (0.47) LMNAHDAC3HDAC4HDAC1HDAC7
Acrylic Acid SCHEMBL5162070 0.67 AKT1 (0.42) AKT1NPSR1TGM2LMNAMEN1
Acrylic Acid SCHEMBL25421985 0.67 MAOB (0.45) LMNAHDAC3HDAC4HDAC1HDAC7
Acrylic Acid SCHEMBL28572675 0.67 MCL1 (0.42) AKT1LMNAHDAC3HDAC4HDAC1
Benzene SCHEMBL28094513 0.67 LMNA (0.56) AKT1TGM2LMNAMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107362387-A A kind of hemostatic material in medical use and preparation method thereof 成都优瑞商务服务有限公司 2017-11-21 CN disclosed