Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL28186901 | 0.76 | AKT1 (0.34) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL296620 | 0.76 | ALDH1A1 (0.48) | NPSR1TRPM8AKT1KDM4EALDH1A1 | |
| SCHEMBL14390570 | 0.75 | HCAR2 (0.46) | HDAC3TNKSHDAC4HDAC1HCAR2 | |
| SCHEMBL8060921 | 0.74 | ESR1 (0.36) | NPSR1AKT1CA2ALDH1A1POLB | |
| SCHEMBL24708669 | 0.74 | MEN1 (0.32) | ALDH1A1POLBKMT2AMEN1HTT | |
| SCHEMBL27724260 | 0.73 | ALDH1A1 (0.36) | NPSR1TRPM8AKT1LMNAALDH1A1 | |
| SCHEMBL11806402 | 0.72 | RECQL (0.46) | HDAC3TNKSHDAC4HDAC1HCAR2 | |
| SCHEMBL11253691 | 0.72 | TRPM8 (0.41) | HDAC3TNKSHDAC4HDAC1HCAR2 | |
| SCHEMBL8060070 | 0.70 | AKR1C3 (0.44) | NPSR1AKT1ALDH1A1POLBKMT2A | |
| Fumaric Acid SCHEMBL21145270 | 0.70 | HCAR2 (0.50) | HDAC3TNKSHDAC4HDAC1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6086764-A | Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use | CROSSWINDS, INC. (US) | 2000-07-11 | — | — | US | claimed |