Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.78 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631409 | 1.00 | DHODH (0.78) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL20956442 | 0.88 | DHODH (1.00) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL29911504 | 0.88 | DHODH (1.00) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL19631441 | 0.88 | DHODH (1.00) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL25614224 | 0.87 | DHODH (0.58) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL19631414 | 0.86 | DHODH (0.95) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL20956482 | 0.86 | DHODH (0.95) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL19631420 | 0.85 | DHODH (0.80) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL20956524 | 0.85 | DHODH (0.80) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL29911542 | 0.85 | DHODH (0.80) | DHODHGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107375279-B | Use of novel thiazole derivatives for the treatment of inflammatory bowel disease | 华东理工大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-107459496-B | Use of thiazole derivatives for treating viral infections | 华东理工大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-107459496-A | Application of the novel thiazole analog derivative in treatment virus infection | 华东理工大学 | 2017-12-12 | — | — | CN | disclosed |
| CN-107375279-A | Application of the novel thiazole analog derivative in inflammatory bowel disease is treated | 华东理工大学 | 2017-11-24 | — | — | CN | disclosed |