Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20555502 | 0.79 | ALDH1A1 (0.49) | ALDH1A1POLBL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL20555279 | 0.78 | POLB (0.40) | ALDH1A1POLBL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL20555449 | 0.78 | ALDH1A1 (0.35) | ALDH1A1POLBL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL16975398 | 0.74 | ALDH1A1 (0.46) | ALDH1A1RECQLPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL20555350 | 0.73 | POLB (0.42) | ALDH1A1POLBL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL26120909 | 0.73 | POLB (0.41) | ALDH1A1POLBL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL16975409 | 0.73 | POLB (0.46) | ALDH1A1POLBL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL16975579 | 0.73 | ALDH1A1 (0.41) | ALDH1A1POLBL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL27439921 | 0.72 | ALDH1A1 (0.40) | ALDH1A1POLBL3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL27918131 | 0.72 | L3MBTL1 (0.35) | ALDH1A1POLBL3MBTL1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105940004-B | Compound | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-02-02 | — | — | CN | disclosed |