Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.31 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258017 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL27321584 | 0.83 | LMNA (0.36) | TSHR | |
| Pyridine SCHEMBL27474885 | 0.73 | CYP1A2 (0.53) | TSHRNAPRTTDP1RECQLF7 | |
| Pyridine SCHEMBL8567227 | 0.73 | NAPRT (0.47) | TSHRNAPRTTDP1RECQLF7 | |
| Pyridine SCHEMBL9065525 | 0.72 | NAPRT (0.60) | TSHRNAPRTTDP1RECQLF7 | |
| Pyridine SCHEMBL1070164 | 0.72 | NAPRT (0.60) | TSHRNAPRTTDP1RECQLF7 | |
| Pyridine SCHEMBL1164077 | 0.72 | NAPRT (0.60) | TSHRNAPRTTDP1RECQLF7 | |
| Pyridine SCHEMBL28243085 | 0.72 | TSHR (0.45) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28762997 | 0.72 | TSHR (0.45) | TSHRNAPRTTDP1RECQLF7 | |
| Pyridine SCHEMBL27497756 | 0.72 | NAPRT (0.45) | TSHRNAPRTTDP1RECQLF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107383239-B | A kind of N- pyridine urea groups chitosan quaternary ammonium salt and its preparation method and application | 中国科学院烟台海岸带研究所 | 2019-06-25 | — | — | CN | claimed |
| CN-108463109-A | Kill harmful organism activity pyrazole derivatives | 先正达参股股份有限公司 | 2018-08-28 | — | — | CN | disclosed |
| CN-107652289-A | Substituted tricyclic compound as FGFR inhibitor | 因塞特控股公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-107383009-A | Substituted tricyclic compound as FGFR inhibitor | 因塞特控股公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-104507943-B | Substituted tricyclic compounds as FGFR inhibitors | 因塞特控股公司 | 2017-11-21 | — | — | CN | disclosed |