SCHEMBL28189692

SCHEMBL28189692

CCCc1ccc(C)c(-c2ccc(O)cc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.55
CNR2 P34972 1/20 0.55
ALOX5 P09917 2/20 0.51
GABRA1 P14867 1/20 0.44
GABRB2 P47870 1/20 0.44
BACE1 P56817 1/20 0.44
ESR1 P03372 5/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
TACR2 P21452 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
CYP3A4 P08684 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
SHBG P04278 1/20 0.42
TP53 P04637 1/20 0.42
HSPD1 P10809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21811720 0.86 CNR1 (0.50) CNR1CNR2ALOX5GABRA1GABRB2
SCHEMBL28061810 0.86 TRPA1 (0.44) ALOX5BACE1ESR1CYP3A4ALDH1A1
SCHEMBL6547024 0.82 PSMB5 (0.50) CNR1CNR2ALOX5BACE1ADORA3
SCHEMBL27579602 0.78 ALOX5 (0.50) CNR1CNR2ALOX5GABRA1GABRB2
SCHEMBL10345396 0.78 ALOX5 (0.50) CNR1CNR2ALOX5GABRA1GABRB2
SCHEMBL21321837 0.78 CNR1 (0.49) CNR1CNR2ALOX5ESR1ADRA2A
SCHEMBL5165125 0.77 CNR1 (0.55) CNR1CNR2ALOX5GABRA1GABRB2
SCHEMBL13464639 0.77 ESR1 (0.59) CNR1CNR2BACE1ESR1ADRA2A
SCHEMBL982274 0.77 ESR1 (0.59) CNR1CNR2BACE1ESR1ADRA2A
SCHEMBL14634079 0.77 APP (0.48) CNR1CNR2ALOX5ESR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107446126-A The manufacture method of polyphenylene oxide 旭化成株式会社 2017-12-08 CN disclosed