SCHEMBL28061810

SCHEMBL28061810

CCc1ccc(C)c(-c2ccc(O)cc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.44
ESRRA P11474 1/20 0.41
GAA P10253 4/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
MAPK1 P28482 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 1/20 0.41
APAF1 O14727 1/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MGAM O43451 3/20 0.39
SI P14410 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28189692 0.86 CNR1 (0.55) ESRRAALDH1A1HSD17B10BACE1ESR2
SCHEMBL9203793 0.83 TRPA1 (0.55) TRPA1GAAALDH1A1MAPTMAPK1
SCHEMBL6013936 0.81 HSD17B1 (0.45) TRPA1ESRRAGAAALDH1A1MAPT
SCHEMBL28112852 0.80 USP7 (0.43) TRPA1GAAALDH1A1MAPTMAPK1
SCHEMBL3669243 0.78 ESR1 (0.50) ESRRAGAAMEN1KMT2AMGAM
SCHEMBL28252223 0.78 HSD17B1 (0.45) TRPA1ESRRAGAAALDH1A1MAPT
SCHEMBL22130621 0.77 MGAM (0.49) GAAMGAMSIMGAM2ALOX5
SCHEMBL11153431 0.77 ALDH1A1 (0.41) ESRRAALDH1A1MEN1HPGDKMT2A
SCHEMBL29637921 0.76 ESRRA (0.61) ESRRAGAAALDH1A1MAPK1MGAM
SCHEMBL20147811 0.76 ESR2 (0.50) ESRRAGAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103154086-B Polyphenylene oxide powder and polyphenyl ether resin composition ASAHI KASEI CHEMICALS CORP. (JP) 2016-05-04 CN disclosed