SCHEMBL28190

SCHEMBL28190

BrCc1cccc2cccc(CBr)c12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
TSHR P16473 5/20 0.45
HSD17B10 Q99714 4/20 0.45
CYP1A2 P05177 3/20 0.45
HPGD P15428 3/20 0.45
CYP3A4 P08684 2/20 0.45
CYP1A1 P04798 1/20 0.45
CYP1B1 Q16678 1/20 0.45
MAPK1 P28482 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ELANE P08246 1/20 0.38
THRB P10828 1/20 0.36
HTR2A P28223 3/20 0.35
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
CES2 O00748 1/20 0.35
BCHE P06276 1/20 0.35
CES1 P23141 1/20 0.35
MCL1 Q07820 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30598018 1.00 ALDH1A1 (0.45) ALDH1A1TSHRHSD17B10CYP1A2HPGD
SCHEMBL5598415 0.92 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10CYP1A2HPGD
SCHEMBL13745202 0.89 TSHR (0.36) ALDH1A1TSHRHSD17B10CYP1A2HPGD
SCHEMBL953211 0.89 GABRA1 (0.48) ALDH1A1TSHRHSD17B10CYP1A2HPGD
SCHEMBL1538927 0.89 ALDH1A1 (0.36) ALDH1A1TSHRHSD17B10CYP1A2HPGD
SCHEMBL23043517 0.85 TSHR (0.38) ALDH1A1TSHRHSD17B10CYP1A2HPGD
SCHEMBL29681001 0.85 TSHR (0.38) ALDH1A1TSHRHSD17B10CYP1A2HPGD
SCHEMBL3283526 0.84 ELANE (0.41) ALDH1A1TSHRHSD17B10CYP1A2HPGD
SCHEMBL8216029 0.79 HTR2A (0.41) ALDH1A1TSHRHSD17B10CYP1A2HPGD
SCHEMBL10582719 0.77 CYP1A2 (0.44) ALDH1A1TSHRHSD17B10CYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7078445-B2 Fluorinated, non-urethane containing multifunctional acrylate from a multifunctional alcohol synthesized from a core of hydroxy-reacting functional groups and a fluorinated molecule with hydroxyl groups, and a photoinitiator E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-07-18 US claimed
JP-11279119-A None JP disclosed
JP-1272530-A None JP disclosed
US-12612473-B2 Polyethylene and its chlorinated polyethylene LG CHEM, LTD. (KR) 2026-04-28 US disclosed
US-12320804-B2 Detection of cleavage activity of an enzyme MOLOGIC LIMITED (GB) 2025-06-03 US disclosed
US-12304976-B2 Polyethylene and chlorinated polyethylene thereof LG CHEM, LTD. (KR) 2025-05-20 US disclosed
US-20250157661-A1 MONITORING INFLAMMATION STATUS MOLOGIC LIMITED (GB) 2025-05-15 US disclosed
EP-3778663-B1 POLYETHYLENE AND CHLORINATED POLYETHYLENE THEREOF LG CHEMICAL LTD (KR) 2024-05-22 EP disclosed
US-11953506-B2 Monitoring inflammation status MOLOGIC LIMITED (GB) 2024-04-09 US disclosed
EP-3928100-B1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION MOLOGIC LTD (GB) 2023-03-22 EP disclosed
EP-0641333-B1 METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS SEARLE & CO (US) 1996-08-14 EP disclosed
WO-1995014653-A1 METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1995-06-01 WO disclosed
EP-0561948-B1 PHOSPHONIC ACID DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS UPJOHN CO (US) 1995-04-05 EP disclosed
EP-0622373-A1 Phosphonic acid derivatives useful as anti-inflammatory agents THE UPJOHN COMPANY (US) 1994-11-02 EP disclosed
US-5360797-A Bisphosphonic acid derivatives useful as anti-arthritic agents THE UPJOHN COMPANY (US) 1994-11-01 US disclosed
US-5298498-A Antiarthritic agents THE UPJOHN COMPANY (US) 1994-03-29 US disclosed
US-5298622-A Spiroindane opiate analogs REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1994-03-29 US disclosed
EP-0561948-A1 PHOSPHONIC ACID DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS. UPJOHN CO (US) 1993-09-29 EP disclosed
WO-1992010504-A2 PHOSPHONIC ACID DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1992-06-25 WO disclosed
JP-H01272530-A PRODUCTION OF CYCLIC ORGANIC COMPOUND BY IRRADIATION WITH LASER AGENCY OF IND SCIENCE & TECHNOL 1989-10-31 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612473-B2 Polyethylene and its chlorinated polyethylene MCM5, PCNA, MKI67 ALDH1A1 3098/4885TSHR 1663/4885HSD17B10 1973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.