Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28190 | 0.89 | ALDH1A1 (0.45) | TSHRALDH1A1HSD17B10CYP3A4CYP1A2 | |
| SCHEMBL30598018 | 0.89 | ALDH1A1 (0.45) | TSHRALDH1A1HSD17B10CYP3A4CYP1A2 | |
| SCHEMBL5598415 | 0.81 | ALDH1A1 (0.50) | TSHRALDH1A1HSD17B10CYP3A4CYP1A2 | |
| SCHEMBL1538927 | 0.78 | ALDH1A1 (0.36) | TSHRALDH1A1HSD17B10CYP3A4CYP1A2 | |
| SCHEMBL953211 | 0.78 | GABRA1 (0.48) | TSHRALDH1A1HSD17B10CYP3A4CYP1A2 | |
| SCHEMBL23043517 | 0.76 | TSHR (0.38) | TSHRALDH1A1HSD17B10CYP3A4CYP1A2 | |
| SCHEMBL29681001 | 0.76 | TSHR (0.38) | TSHRALDH1A1HSD17B10CYP3A4CYP1A2 | |
| SCHEMBL3283526 | 0.74 | ELANE (0.41) | TSHRALDH1A1HSD17B10CYP3A4CYP1A2 | |
| SCHEMBL7886954 | 0.74 | TRPA1 (0.39) | TSHRALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL18436948 | 0.73 | GABRA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572874-B2 | Processes based on atom (or group) transfer radical polymerization and novel (co)polymers having useful structures and properties | CARNEGIE MELLON UNIVERSITY (US) | 2009-08-11 | — | — | US | disclosed |