Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 5/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689571 | 0.76 | MCL1 (0.53) | TDP1ALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL12355749 | 0.74 | ALKBH5 (0.40) | CYP2A6TDP1MEN1KMT2ALMNA | |
| SCHEMBL689572 | 0.72 | PTGDR2 (0.38) | CYP2A6TDP1MEN1KMT2ALMNA | |
| SCHEMBL690926 | 0.69 | CYP2A6 (0.41) | CYP2A6TDP1MEN1KMT2ALMNA | |
| SCHEMBL29935861 | 0.69 | CYP2A6 (0.41) | CYP2A6TDP1MEN1KMT2ALMNA | |
| SCHEMBL29569282 | 0.67 | CYP2A6 (0.37) | CYP2A6TDP1MEN1KMT2ALMNA | |
| SCHEMBL19584788 | 0.67 | CYP2A6 (0.37) | CYP2A6TDP1MEN1KMT2ALMNA | |
| SCHEMBL28045310 | 0.66 | MEN1 (0.39) | CYP2A6TDP1MEN1KMT2ALMNA | |
| SCHEMBL27969744 | 0.64 | ALDH1A1 (0.34) | ALDH1A1ERN1KDM4E | |
| SCHEMBL13561990 | 0.63 | ALDH1A1 (0.38) | CYP2A6TDP1LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209444-B | It can be used as the benzo-fused heterocycle derivative of GPR120 activator | 詹森药业有限公司 | 2017-12-29 | — | — | CN | disclosed |