Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690926 | 0.77 | CYP2A6 (0.41) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL29935861 | 0.77 | CYP2A6 (0.41) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL2054120 | 0.68 | APP (0.36) | TDP1ERN1ALDH1A1APPTLR2 | |
| SCHEMBL981676 | 0.65 | LMNA (0.55) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL19584788 | 0.63 | CYP2A6 (0.37) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL4944634 | 0.63 | THRB (0.52) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL3794351 | 0.62 | TDP1 (0.58) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL31691122 | 0.61 | SLC40A1 (0.43) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL3432484 | 0.61 | SLC40A1 (0.43) | MEN1KMT2ATDP1LMNATHRB | |
| SCHEMBL9005 | 0.61 | MEN1 (0.57) | MEN1KMT2ATDP1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209444-A | Benzo-fused heterocyclic derivatives useful as agonists of GPR120 | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |