SCHEMBL28190337

SCHEMBL28190337

O=CC(C(=O)c1ccccc1)c1ccco1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.46
POLB P06746 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
PKM P14618 1/20 0.46
PTPN1 P18031 1/20 0.46
PTPN7 P35236 1/20 0.46
BLM P54132 1/20 0.46
ESR2 Q92731 1/20 0.46
MIF P14174 1/20 0.44
ALDH1A1 P00352 4/20 0.42
MEN1 O00255 3/20 0.42
AGTR1 P30556 1/20 0.42
CYP2C19 P33261 1/20 0.41
MDM2 Q00987 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
HSD17B10 Q99714 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CES2 O00748 1/20 0.39
LMNA P02545 1/20 0.39
CES1 P23141 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27533473 0.81 KMT2A (0.61) KMT2APOLBL3MBTL1PKMPTPN1
SCHEMBL4577407 0.77 KMT2A (0.47) KMT2APOLBL3MBTL1PKMPTPN1
SCHEMBL29241351 0.77 KMT2A (0.66) KMT2APOLBL3MBTL1PKMPTPN1
SCHEMBL1554954 0.76 TDP1 (0.57) POLBL3MBTL1ALDH1A1MDM2TDP1
SCHEMBL10338542 0.75 KMT2A (0.48) KMT2APOLBL3MBTL1PKMPTPN1
SCHEMBL28853906 0.75 KMT2A (0.53) KMT2APOLBL3MBTL1PKMPTPN1
SCHEMBL28254789 0.75 KMT2A (0.48) KMT2APOLBL3MBTL1PKMPTPN1
Isopropyl Alcohol SCHEMBL28255035 0.70 LMNA (0.53) L3MBTL1ALDH1A1CYP2C19MDM2TDP1
SCHEMBL1061459 0.70 MAPT (0.43) KMT2APOLBL3MBTL1PKMPTPN1
SCHEMBL9461930 0.70 KMT2A (0.47) KMT2APOLBL3MBTL1PKMPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107522681-A The fused heterocyclic compound of group containing intermolecular proton transfer and preparation method and its application as embedded photoluminescent material 陕西师范大学 2017-12-29 CN disclosed