Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554954 | 0.93 | TDP1 (0.57) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL9816220 | 0.86 | CYP2C9 (0.45) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL28053531 | 0.81 | CES2 (0.48) | LMNACES2CES1TDP1L3MBTL1 | |
| Benzoin SCHEMBL319403 | 0.77 | LMNA (0.88) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL19984712 | 0.76 | LMNA (0.59) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL7192990 | 0.75 | TDP1 (0.50) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL5224169 | 0.75 | PGR (0.48) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL9662050 | 0.75 | CYP2D6 (0.48) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL5859278 | 0.75 | UGT2B7 (0.43) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL5858504 | 0.75 | CES2 (0.50) | CES2CES1TDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640894-B | two-component polyurethane composition | SIKA技术股份公司 | 2018-11-13 | — | — | CN | disclosed |