Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL28255035 | 0.93 | LMNA (0.53) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL28053531 | 0.87 | CES2 (0.48) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL9816220 | 0.86 | CYP2C9 (0.45) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL5858504 | 0.81 | CES2 (0.50) | TDP1CES2CES1ALDH1A1CYP3A4 | |
| SCHEMBL5859278 | 0.81 | UGT2B7 (0.43) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL25121338 | 0.80 | CYP1A2 (0.59) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL1302046 | 0.80 | CYP1A2 (0.59) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL28459036 | 0.80 | CYP2D6 (0.52) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL31606754 | 0.77 | CYP1A2 (0.71) | TDP1L3MBTL1LMNACES2CES1 | |
| SCHEMBL10842354 | 0.77 | CYP2D6 (0.48) | TDP1L3MBTL1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721918-A | A kind of flexible rare-earth transparent luminous film and preparation method thereof applied to silica-based solar cell | 河北工业大学 | 2019-05-07 | — | — | CN | claimed |
| CN-107354952-A | A kind of installation method of mountain area steep slope region Road Bridge Pile Foundation | 李建龙 | 2017-11-17 | — | — | CN | claimed |
| CN-106633033-A | Intrinsic microporous copolymer containing phthalazinone biphenyl structure and preparation method thereof | 大连理工大学 | 2017-05-10 | — | — | CN | claimed |
| CN-103459467-B | Polybenzoxazole resin and precursor thereof | MITSUBISHI GAS CHEMICAL CO.,INC. (JP) | 2016-04-06 | — | — | CN | claimed |
| CN-104559130-A | TPU (thermoplastic polyurethane) mobile phone protective case and preparation method thereof | JIANGSU MACRO GREEN MATERIAL TECHNOLOGY CO LTD | 2015-04-29 | — | — | CN | claimed |
| CN-104193742-A | Synthetic method of 3-alkyl substituent-7-azaindole compound | UNIV CHINA WEST NORMAL | 2014-12-10 | — | — | CN | claimed |
| CN-103952552-A | Preparation method of copper extracting agent LPB | SICHUAN ZHIJIANG ADVANCED MATERIALS CO LTD | 2014-07-30 | — | — | CN | claimed |
| EP-1463513-A1 | STABILIZED BRIVUDINE TOPICAL FORMULATIONS | Menarini Ricerche S.p.A. (IT) | 2004-10-06 | — | — | EP | claimed |
| WO-2003051375-A1 | STABILIZED BRIVUDINE TOPICAL FORMULATIONS | MENARINI RICERCHE S.P.A. (IT) | 2003-06-26 | — | — | WO | claimed |
| CN-116285787-A | Adhesive composition and adhesive sheet for display comprising same | 利诺士尖端材料有限公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-3342767-B1 | PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2021-04-14 | — | — | EP | disclosed |
| US-20200392123-A1 | PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2020-12-17 | — | — | US | disclosed |
| US-10689372-B2 | Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2020-06-23 | — | — | US | disclosed |
| CN-107785169-B | Solid electrolytic capacitor element, solid electrolytic capacitor and its manufacturing method | 株式会社村田制作所 | 2019-11-22 | — | — | CN | disclosed |
| WO-1996021650-A1 | PROCESS FOR PRODUCING 3,5-DIARYL PYRAZOLENE | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-18 | — | — | WO | disclosed |
| EP-0626969-A4 | CoA-IT AND PAF INHIBITORS. | SMITHKLINE BEECHAM CORP (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0626969-A1 | CoA-IT AND PAF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993016674-A1 | CoA-IT AND PAF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-02 | — | — | WO | disclosed |
| EP-0548227-A1 | COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992004334-A1 | COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689372-B2 | Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto | PTGIR, PTGIS, PTGER1 | TDP1 1990/4885L3MBTL1 4819/4885LMNA 2865/4885 |
| US-20200392123-A1 | PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | PTGIR, PTGIS, PTGER1 | TDP1 1990/4885L3MBTL1 4819/4885LMNA 2865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.