Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | MST1R | Q04912 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17673285 | 0.71 | CES1 (0.39) | SMN1; SMN2CMA1GSK3AGSK3BACVR1 | |
| SCHEMBL15046641 | 0.69 | CCR1 (0.45) | SMN1; SMN2GSK3AGSK3BACVR1MST1R | |
| SCHEMBL30174440 | 0.69 | ADRB2 (0.52) | CCNCCDK8SMN1; SMN2GSK3AGSK3B | |
| SCHEMBL22854 | 0.69 | ADRB2 (0.52) | CCNCCDK8SMN1; SMN2GSK3AGSK3B | |
| SCHEMBL15219374 | 0.68 | ROCK1 (0.49) | SMN1; SMN2CCR1CCR5CCR8 | |
| SCHEMBL14423294 | 0.68 | CCR1 (0.44) | SMN1; SMN2ACVR1TLR8CCR1CCR5 | |
| SCHEMBL24338668 | 0.67 | LOXL2 (0.46) | SMN1; SMN2CCR1CCR5CCR8KDM4E | |
| SCHEMBL17785563 | 0.67 | TRPA1 (0.43) | SMN1; SMN2CMA1CLK4TLR8KDM4E | |
| SCHEMBL7003951 | 0.65 | CCR1 (0.44) | SMN1; SMN2TLR8CCR1CCR5CCR8 | |
| Trifluoroacetic Acid SCHEMBL28101328 | 0.65 | SMN1; SMN2 (0.44) | SMN1; SMN2PTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531690-A | The amines of 4,5,6,7 tetrahydrochysene 1H pyrazolos [4,3 c] pyridine 3 as CBP and/or EP300 inhibitor | 基因泰克公司 | 2018-01-02 | — | — | CN | disclosed |