Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10957215 | 0.87 | ALDH1A1 (0.32) | ALDH1A1GAA | |
| SCHEMBL28192758 | 0.85 | MAPT (0.43) | MAPTHTTMAPK1ALDH1A1GAA | |
| SCHEMBL28192154 | 0.84 | MAPT (0.41) | MAPTALDH1A1TP53NPSR1 | |
| SCHEMBL30913234 | 0.82 | L3MBTL1 (0.34) | MAPTHTTMAPK1ALDH1A1CYP2A6 | |
| SCHEMBL28324686 | 0.77 | ALDH1A1 (0.38) | MAPTHTTALDH1A1GAANPSR1 | |
| SCHEMBL28324633 | 0.77 | GAA (0.35) | MAPTMAPK1ALDH1A1GAATDP1 | |
| SCHEMBL28324627 | 0.77 | GAA (0.38) | MAPTMAPK1ALDH1A1GAATDP1 | |
| SCHEMBL28192176 | 0.77 | PRKCZ (0.38) | MAPTGAA | |
| SCHEMBL28192157 | 0.77 | KMT2A (0.38) | MAPTMAPK1ALDH1A1GAA | |
| SCHEMBL28854127 | 0.76 | L3MBTL1 (0.39) | MAPTHTTALDH1A1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417628-A | Diaryl quianzolinones, its preparation method and its medical usage and the pharmaceutical composition comprising such compound | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-12-01 | — | — | CN | claimed |
| CN-107417628-A | Diaryl quianzolinones, its preparation method and its medical usage and the pharmaceutical composition comprising such compound | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-12-01 | — | — | CN | disclosed |