SCHEMBL28192196

SCHEMBL28192196

O=C(O)Cc1cc(=O)cc[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.46
ALDH1A1 P00352 5/20 0.42
TSHR P16473 4/20 0.42
NFKB1 P19838 3/20 0.42
CYP3A4 P08684 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRR1 P24046 1/20 0.42
GABRR2 P28476 1/20 0.42
GABRA5 P31644 1/20 0.42
GABRB2 P47870 1/20 0.42
GABRA4 P48169 1/20 0.42
KDM4E B2RXH2 5/20 0.41
MAPT P10636 3/20 0.41
PMP22 Q01453 3/20 0.41
AKR1B1 P15121 2/20 0.37
HPGD P15428 4/20 0.36
HSD17B10 Q99714 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ENPP2 Q13822 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7092113 0.82 GPR84 (0.44) GPR84ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL11504164 0.82 GPR84 (0.44) GPR84ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL253592 0.74
Acetic Acid SCHEMBL31668831 0.73 GPR84 (0.62) GPR84ALDH1A1TSHRKDM4EHPGD
Hydrochloric Acid SCHEMBL6546575 0.72 ALDH1A1 (0.47) ALDH1A1TSHRNFKB1CYP3A4GABRA1
Bromide SCHEMBL27470986 0.72 TSHR (0.46) ALDH1A1TSHRNFKB1CYP3A4GABRA1
SCHEMBL27042187 0.71
SCHEMBL9164438 0.71
SCHEMBL8713689 0.69 GPR84 (0.62) GPR84ALDH1A1TSHRKDM4ECA2
SCHEMBL28127868 0.69 DAO (0.50) GPR84TSHRCYP3A4HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531614-A De Luogewei preparation method 迈兰实验室有限公司 2018-01-02 CN disclosed