Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 6/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31307738 | 0.90 | KLKB1 (0.51) | KLKB1GRM2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL553953 | 0.85 | KLKB1 (0.58) | KLKB1GRM2NPC1 | |
| SCHEMBL553848 | 0.85 | ALDH1A1 (0.60) | KLKB1GRM2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2822906 | 0.84 | ALDH1A1 (0.53) | GRM2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1909166 | 0.83 | GRM2 (0.53) | KLKB1GRM2KDM4ENPC1MEN1 | |
| SCHEMBL4771423 | 0.82 | MEN1 (0.62) | KLKB1GRM2KDM4EMEN1KMT2A | |
| SCHEMBL2821953 | 0.82 | LMNA (0.54) | KLKB1GRM2NPC1ALDH1A1LMNA | |
| SCHEMBL554179 | 0.82 | KLKB1 (0.55) | KLKB1MEN1KMT2A | |
| SCHEMBL28595790 | 0.82 | ESR1 (0.55) | KLKB1GRM2KDM4ENPC1MEN1 | |
| SCHEMBL3606832 | 0.82 | SMN1; SMN2 (0.57) | KLKB1GRM2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | KLKB1 1854/4885GRM2 849/4885KDM4E 4620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.