Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CD74 | P04233 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30119596 | 0.89 | KMT2A (0.48) | MEN1KMT2AKLKB1HPGDSMN1; SMN2 | |
| SCHEMBL28604358 | 0.89 | KMT2A (0.48) | MEN1KMT2AKLKB1HPGDSMN1; SMN2 | |
| SCHEMBL28587535 | 0.86 | SMN1; SMN2 (0.50) | MEN1KMT2AKLKB1HPGDSMN1; SMN2 | |
| SCHEMBL30119622 | 0.86 | SMN1; SMN2 (0.50) | MEN1KMT2AKLKB1HPGDSMN1; SMN2 | |
| SCHEMBL15154992 | 0.85 | KMT2A (0.68) | MEN1KMT2AKLKB1ALDH1A1MAPT | |
| SCHEMBL369369 | 0.85 | L3MBTL1 (0.54) | MEN1KMT2AKLKB1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4767882 | 0.85 | GRM2 (0.56) | KMT2AKLKB1HPGDSMN1; SMN2GRM2 | |
| SCHEMBL31591067 | 0.84 | KLKB1 (0.58) | MEN1KMT2AKLKB1HPGDSMN1; SMN2 | |
| SCHEMBL30739140 | 0.84 | KLKB1 (0.58) | MEN1KMT2AKLKB1HPGDSMN1; SMN2 | |
| SCHEMBL553848 | 0.84 | ALDH1A1 (0.60) | KLKB1SMN1; SMN2ALDH1A1GRM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373832-B | Macrocyclic compound, pharmaceutical composition and application thereof | 深圳晶蛋生物医药科技有限公司 | 2025-01-28 | — | — | CN | disclosed |
| WO-2024153028-A1 | MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 深圳晶蛋生物医药科技有限公司 | 2024-07-25 | — | — | WO | disclosed |
| CN-118373832-A | Macrocyclic compound, pharmaceutical composition and application thereof | 深圳晶蛋生物医药科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| EP-1678181-B1 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS INC (US) | 2008-12-31 | — | — | EP | disclosed |
| US-7449473-B2 | Substituted pyrrolo[3,2-d]pyrimidin-2,4-diones as A2b adenosine receptor antagonists | CV THERAPEUTICS, INC. (US) | 2008-11-11 | — | — | US | disclosed |
| EP-1678181-A2 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2006-07-12 | — | — | EP | disclosed |
| US-20050119287-A1 | A2B adenosine receptor antagonists | GILEAD PALO ALTO, INC. | 2005-06-02 | — | — | US | disclosed |
| WO-2005042534-A2 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119287-A1 | A2B adenosine receptor antagonists | ADORA2B, ADORA2A, ADORA3 | MEN1 4726/4885KMT2A 1806/4885KLKB1 2283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.