Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.74 |
| ▸ | RAB9A | P51151 | 8/20 | 0.74 |
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | STAT1 | P42224 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.67 |
| ▸ | RELA | Q04206 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210881 | 0.85 | ALDH1A1 (0.74) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7210871 | 0.85 | ALDH1A1 (0.74) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL4016837 | 0.84 | ALDH1A1 (0.66) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL4016843 | 0.84 | ALDH1A1 (0.66) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL13556270 | 0.84 | RAB9A (0.72) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL3456494 | 0.81 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL789554 | 0.80 | ALDH1A1 (0.71) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29449730 | 0.80 | ALDH1A1 (0.71) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL8181176 | 0.80 | MAPT (0.66) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1590018 | 0.80 | ALDH1A1 (0.69) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107628981-B | A kind of cinnamoyl sulfonylindoline compounds and its application for preparing glaucoma medicine | 威海市妇女儿童医院 | 2019-07-30 | — | — | CN | disclosed |
| CN-107628981-A | A kind of cinnamoyl sulfonylindoline compounds and its application for preparing glaucoma medicine | 威海市妇女儿童医院 | 2018-01-26 | — | — | CN | disclosed |