Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.62 |
| ▸ | RELA | Q04206 | 4/20 | 0.62 |
| ▸ | PKM | P14618 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016843 | 1.00 | ALDH1A1 (0.66) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL4017497 | 0.91 | SMN1; SMN2 (0.65) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL4017502 | 0.91 | SMN1; SMN2 (0.65) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL28195698 | 0.84 | ALDH1A1 (0.74) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL789554 | 0.83 | ALDH1A1 (0.71) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL29449730 | 0.83 | ALDH1A1 (0.71) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL5492983 | 0.81 | NOTUM (0.64) | ALDH1A1LMNANPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL10741975 | 0.81 | ALDH1A1 (0.69) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL30538003 | 0.81 | ALDH1A1 (0.66) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL10899996 | 0.80 | NOTUM (0.62) | ALDH1A1LMNANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482379-B2 | Propenoyl hydrazides | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-01-27 | — | — | US | disclosed |
| US-20050256058-A1 | Propenoyl hydrazides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256058-A1 | Propenoyl hydrazides | DNPEP, HPN, PREP | ALDH1A1 2687/4885LMNA 2599/4885NPC1 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.