Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 4/20 | 0.45 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466757 | 0.86 | SENP1 (0.48) | USP7SENP1ESR1ESR2PDE4A | |
| SCHEMBL29392999 | 0.86 | SENP1 (0.48) | USP7SENP1ESR1ESR2PDE4A | |
| SCHEMBL5581681 | 0.81 | SENP1 (0.45) | USP7SENP1ESR1ESR2PDE4A | |
| SCHEMBL1073583 | 0.78 | GABRA1 (0.54) | USP7SENP1ESR1ESR2PDE4A | |
| SCHEMBL28119491 | 0.76 | GABRA1 (0.52) | USP7SENP1ESR1ESR2PDE4A | |
| SCHEMBL2551509 | 0.74 | USP7 (0.54) | USP7SENP1ESR1ESR2PDE4A | |
| SCHEMBL11223665 | 0.73 | GABRA1 (0.52) | USP7SENP1ESR1ESR2PDE4A | |
| SCHEMBL31402580 | 0.73 | HSD17B1 (0.39) | USP7SENP1ESR1ESR2HSD17B1 | |
| SCHEMBL28308128 | 0.73 | PREP (0.38) | USP7SENP1ESR1ESR2PDE4A | |
| SCHEMBL113297 | 0.73 | TDP1 (0.46) | ALDH1A1HSD17B10HPGDKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531652-A | Aromatic diamine, intermediate thereof, and processes for producing these | 精化株式会社 | 2018-01-02 | — | — | CN | disclosed |