SCHEMBL28196475

SCHEMBL28196475

O=C(O)C1(C(=O)O)CCC1C1CCCNC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 4/20 0.43
SLC6A11 P48066 3/20 0.43
SLC6A13 Q9NSD5 3/20 0.43
TSHR P16473 1/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
ATM Q13315 1/20 0.38
CYP2D6 P10635 1/20 0.38
CPN1 P15169 2/20 0.35
CPB2 Q96IY4 2/20 0.35
ARG1 P05089 2/20 0.32
ARG2 P78540 2/20 0.32
APLNR P35414 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRB2 P47870 2/20 0.31
SLC6A12 P48065 2/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28991427 0.74 HSD11B1 (0.31)
SCHEMBL75178 0.70 CYP2C19 (0.34)
Hydrochloric Acid SCHEMBL3684435 0.68 CYP2C19 (0.33)
SCHEMBL660990 0.67 SLC6A1 (0.44) SLC6A1SLC6A11SLC6A13TSHRLMNA
SCHEMBL19816795 0.64 SLC6A1 (0.46) SLC6A1SLC6A11SLC6A13TSHRLMNA
SCHEMBL19816548 0.64 SLC6A1 (0.46) SLC6A1SLC6A11SLC6A13TSHRLMNA
SCHEMBL19816545 0.64 SLC6A1 (0.46) SLC6A1SLC6A11SLC6A13TSHRLMNA
Bicarbonate SCHEMBL5698068 0.63 SLC6A1 (0.43) SLC6A1SLC6A11SLC6A13TSHRLMNA
SCHEMBL29058488 0.63 SLC6A1 (0.44) SLC6A1SLC6A11SLC6A13TSHRLMNA
SCHEMBL26122200 0.63 SLC6A1 (0.44) SLC6A1SLC6A11SLC6A13TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104995201-B Platinum (II) compound for treating tumor cell proliferative diseases 北京市丰硕维康技术开发有限责任公司 2017-12-22 CN disclosed