Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichloroacetic Acid SCHEMBL10540554 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53LMNAHSD17B10 | |
| Ether SCHEMBL8831321 | 0.82 | — | — | |
| Ether SCHEMBL11546234 | 0.79 | — | — | |
| Ether SCHEMBL10563710 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53LMNAHSD17B10 | |
| Ether SCHEMBL28227566 | 0.78 | — | — | |
| Dalapon SCHEMBL5693111 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRTP53LMNAHSD17B10 | |
| Ether SCHEMBL1811583 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TSHRLMNA | |
| Ether SCHEMBL4973856 | 0.74 | — | — | |
| SCHEMBL28104640 | 0.74 | ALDH1A1 (0.54) | ALDH1A1TSHRTP53 | |
| SCHEMBL20973 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814046-B | Imidazopyridine derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-01-30 | — | — | CN | disclosed |