Trichloroacetic Acid

Trichloroacetic Acid

SCHEMBL10540554

CCOCC.O=C(O)C(Cl)(Cl)Cl

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
TSHR P16473 4/20 0.56
TP53 P04637 1/20 0.56
FFAR3 O14843 1/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
SOAT1 P35610 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dalapon SCHEMBL5693111 0.86 ALDH1A1 (0.38) ALDH1A1TSHRTP53FFAR3LMNA
Ether SCHEMBL28196813 0.83 ALDH1A1 (0.37) ALDH1A1TSHRTP53LMNAHSD17B10
Pivalate SCHEMBL11039116 0.80 ALDH1A1 (0.40) ALDH1A1TSHRFFAR3LMNAHSD17B10
Trichloroacetic Acid SCHEMBL2699210 0.79 ALDH1A1 (0.67) ALDH1A1TSHRTP53FFAR3THRB
Ether SCHEMBL11546234 0.79
Ether SCHEMBL9339223 0.78 ALDH1A1 (0.46) ALDH1A1TSHRFFAR3LMNAHSD17B10
Ether SCHEMBL613941 0.78
Trifluoroacetic Acid SCHEMBL8383456 0.78 FAAH (0.41) ALDH1A1TSHRFFAR3HSD17B10
Ether SCHEMBL9798441 0.77 HMGCR (0.39) ALDH1A1TSHRFFAR3CYP2D6CYP2C19
Trichloroacetic Acid SCHEMBL10369550 0.77 ALDH1A1 (0.67) ALDH1A1TSHRTP53LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4871523-A HALOGENATED ORGANIC COMPOUNDS; CATALYST FOR OLEFIN COPOLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1989-10-03 US claimed
EP-0291359-A2 Vanadium tetrachloride stabilization EXXON CHEMICAL PATENTS INC. (US) 1988-11-17 EP claimed
CN-113801249-B Preparation method of prepared rehmannia root polysaccharide, product and application of prepared rehmannia root polysaccharide 河南中医药大学 2023-01-24 CN disclosed
CN-111944734-B Method for improving yield of streptomycete polyketide 中国科学院微生物研究所 2023-01-10 CN disclosed
CN-111944734-A Method for improving yield of streptomycete polyketide 中国科学院微生物研究所 2020-11-17 CN disclosed