Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichloroacetic Acid SCHEMBL10540554 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53CYP2D6CYP2C19 | |
| Pivalate SCHEMBL11039116 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| Dalapon SCHEMBL45164 | 0.80 | — | — | |
| Dalapon SCHEMBL4895986 | 0.80 | TSHR (0.57) | ALDH1A1TSHRTP53CYP2D6CYP2C19 | |
| Ether SCHEMBL11546234 | 0.77 | — | — | |
| Dalapon SCHEMBL11048266 | 0.76 | — | — | |
| Ether SCHEMBL9339223 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2D6LMNAHSD17B10 | |
| Dalapon SCHEMBL4453180 | 0.76 | — | — | |
| Ether SCHEMBL613941 | 0.76 | — | — | |
| Dalapon SCHEMBL2586474 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200215118-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF ATOPY CONTAINING EXOSOMES DERIVED FROM NEURAL STEM CELLS | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2020-07-09 | — | — | US | disclosed |
| EP-1653920-A1 | COSMETIC COMPOSITIONS CONTAINING FULLERENE CLUSTERS | Burangulov, Nail (RU) | 2006-05-10 | — | — | EP | disclosed |
| WO-2006001784-A1 | COSMETIC COMPOSITIONS CONTAINING FULLERENE CLUSTERS | BURANGULOV NAIL (RU) | 2006-01-05 | — | — | WO | disclosed |
| US-20050136079-A1 | Cosmetic compositions containing fullerene clusters | FULLERENCE INTERNATIONAL CORPORATION | 2005-06-23 | — | — | US | disclosed |