Benzene

Benzene

SCHEMBL28196864

C=CC(O)c1ccccc1.c1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 4/20 0.42
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
HIF1A Q16665 1/20 0.39
HPGD P15428 1/20 0.39
RIPK1 Q13546 1/20 0.39
CYP2D6 P10635 1/20 0.39
SRC P12931 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL96576 1.00 TSHR (0.43) TSHRALDH1A1LMNAMAPK1CYP2C19
SCHEMBL3893413 1.00 TSHR (0.43) TSHRALDH1A1LMNAMAPK1CYP2C19
SCHEMBL13090620 1.00 TSHR (0.43) TSHRALDH1A1LMNAMAPK1CYP2C19
Ammonia Solution, Strong SCHEMBL5430573 0.97 TSHR (0.42) TSHRALDH1A1LMNAMAPK1CYP2C19
SCHEMBL28492568 0.86 CYP3A4 (0.46) ALDH1A1CYP2D6
Acrylamide SCHEMBL6244745 0.85 ALDH1A1 (0.42) TSHRALDH1A1LMNAMAPK1CYP2C19
SCHEMBL6244742 0.82 KDM4E (0.37) TSHRALDH1A1LMNAMAPK1CYP2C19
SCHEMBL9814678 0.82 PGK1 (0.41) TSHRALDH1A1LMNAMAPK1CYP2C19
SCHEMBL14149737 0.81 ALDH1A1 (0.42) TSHRALDH1A1LMNACYP2C19KDM4E
SCHEMBL8621423 0.81 CALM1 (0.46) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107641076-A A kind of synthetic method of luxuriant and rich with fragrance quinones 浙江工业大学 2018-01-30 CN claimed
CN-107641076-A A kind of synthetic method of luxuriant and rich with fragrance quinones 浙江工业大学 2018-01-30 CN disclosed