Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 8/20 | 0.34 |
| ▸ | METAP1 | P53582 | 6/20 | 0.34 |
| ▸ | FBP1 | P09467 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20181855 | 0.86 | TDP1 (0.39) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL20144184 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL21343018 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL19235724 | 0.81 | BTN3A1 (0.36) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL28197101 | 0.80 | BTN3A1 (0.34) | ALDH1A1TSHRBTN3A1FBP1 | |
| SCHEMBL25893454 | 0.77 | BTN3A1 (0.41) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL12746435 | 0.77 | MGAM (0.39) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL20181544 | 0.77 | MGAM (0.39) | ALDH1A1HSD17B10BTN3A1MGAMGAA | |
| SCHEMBL19225305 | 0.77 | MGAM (0.39) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL13633863 | 0.77 | MGAM (0.39) | ALDH1A1CYP3A4ALOX15TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709288-A | Phosphamide derivative and preparation method and application thereof | 四川海思科制药有限公司 | 2018-02-16 | — | — | CN | disclosed |